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UHM Journal-Based CME Volume 47, Issue 2

Table of Contents: RESEARCH ARTICLERoflumilast, a phosphodiesterase-4 inhibitor, improves hyperoxia-induced lung injury via anti-inflammationHong-Ying Cao; Tian-Hua Yu; Cui-Hong Han; Wen-Wu Liu; Pei-Xi Zhang; Peng Tang RESEARCH ARTICLEWhole-body active heating does not preserve finger temperature or ...Read more

  • Course Description
  • Course Credits

Table of Contents:

Roflumilast, a phosphodiesterase-4 inhibitor, improves hyperoxia-induced lung injury via anti-inflammation
Hong-Ying Cao; Tian-Hua Yu; Cui-Hong Han; Wen-Wu Liu; Pei-Xi Zhang; Peng Tang

Whole-body active heating does not preserve finger temperature or manual dexterity during cold-water immersion
Courtney E. Wheelock, MS; Hayden W Hess, MS; Zachary J. Schlader, PhD; Blair D. Johnson, PhD; David Hostler, PhD


  1. To understand the cause of hyperoxia induced lung injury. 
  2. To explain the pathogenesis, pathology and clinical manifestation of hyperoxia induced lung injury. 
  3. To evaluate gross and fine manual dexterity during cold water immersion as a function of time and skin temperature.
  4. To determine if whole-body active heating with warm water perfusion is able to attenuate the reduction in hand and finger skin temperature and preserve dexterity.
  5. To explain the effects of roflumilast on hyperoxia induced acute lung injury in a rat model.


“The process to identify and disclose to learners the relevant financial relationships of the article’s authors and editors or to resolve their conflicts of interest is handled by the Journal Editors. Disclosure by authors is a standard component of published articles, and the editorial review process manages the resolution of any conflicts of interest. The UHMS Education Committee does identify, resolve and disclose relevant financial relationships for those involved in planning the journal-based CME activity evaluation mechanism and they are listed below.”

All individuals in control of content for this educational activity with their relevant financial relationship disclosed are listed below (if applicable). An individual who refuses to disclose relevant financial relationships will be disqualified from being in control of educational content at any time, and cannot have control of, or responsibility for, the development, management, presentation, or evaluation of the CME activity.

Financial relationships are relevant if the following three conditions are met for the individual who will control content of the education:

  1. A financial relationship, in any amount, exists between the person in control of content and an ineligible company.
  2. The content of the education is related to the products of an ineligible company with whom the person has a financial relationship.
  3. The financial relationship existed during the past 24 months

“None of the individuals in control of content (planners/faculty/reviewers/authors) for this educational activity have relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.”

No commercial support was received for this activity.

The content has been reviewed and is free of commercial bias. Any relevant relationships noted have been resolved prior to the start of the activity.

This activity reports no commercial support.


  • Non-Member: $45.00
  • Regular UHMS Member: $35.00
  • Associate UHMS Member: $25.00


For over 45 years the UHMS has been the primary source of information for hyperbaric medicine and physiology worldwide.  This evidence based, peer-reviewed scientific  journal-based CME has as its goal to address identified professional practice gaps and provide a quality CME opportunity which will improve scientific knowledge and skills for undersea,  hyperbaric and wound care physicians, nurses and technicians, and other clinicians and personnel whose practice includes undersea, hyperbaric medicine and wound care.

Target Audience – Included in the “goal”

Date of the activity’s original release – December 16, 2021

Termination date – December 16, 2024

Accreditation Statement: The Undersea and Hyperbaric Medical Society is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation Statements: 

Physician CME: The Undersea & Hyperbaric Medical Society designates this journal-based activity for a maximum of 2 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

MOC ABPM: The American Board of Preventive Medicine (ABPM) has approved this activity for a maximum of 2 LLSA credits towards ABPM MOC Part II requirements.

Nursing/RRT Contact: Hours: 2

License types: RN, LPN, CNS, ARNP, CAN. Provided through the Florida State Board of Nursing and the CE is reciprocal for nurses in the United States. Florida nursing credits are reciprocal and approved for nurses within all states. Receiving credit for Florida providers is simple, attend the course and our staff will upload your credits directly to the Florida State database. For out of state credit, we provide all the necessary paperwork for you to file with the respective nursing board.

Full Disclosure Statement: All faculty members and planners participating in continuing medical education activities sponsored by UHMS are expected to disclose to the participants any relevant financial relationships with commercial interests. Full disclosure of faculty and planner relevant financial relationships will be made at the activity.

UHMS Disclaimer: The information provided at this CME activity is for Continuing Medical Education purposes only.  The lecture content, statements or opinions expressed however, do not necessarily represent those of the Undersea and Hyperbaric Medical Society (UHMS), its affiliates or its employees.

Hardware/Software Requirements:

Hardware required for a learner to participate in this journal-based enduring material activity includes:

Computer with internet connection and a modern, updated browser

Note: If using IE 6, IE 7, or IE 8 we cannot guarantee that the courses will work.

Keyboard to take the quizzes

This journal-based Internet Enduring Material activity is produced for online use.

Provider Contact Information

If at any time during participation in this online CME enduring material event, a learner can contact UHMS, by clicking on "Contact Us" tab located on the far right hand side of the main menu bar found at the top of the screen. Also, the contact phone number and email address (hotlink) is always displayed on the top center of the screen, under the main menu bar.

Undersea and Hyperbaric Medical Society (UHMS)

631 U.S. Highway 1, Suite 307

North Palm Beach, FL 33408

Phone: +1-919-490-5140/877-533-8467

Fax: +1-919-490-5140


Copyright © 2019 Undersea & Hyperbaric Medical Society, Inc.  Undersea and Hyperbaric Medicine is a publication of the Undersea and Hyperbaric Medical Society, Inc., which holds the copyright thereto.  No portion of this publication may be reproduced, displayed or transmitted in any form or using any information storage and retrieval system including photocopying (except for personal use) without prior written permission of the copyright owner